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Testing for Norwalk-like viruses at the State Health Department Level: A Valuable Tool for Identifying the Agent for Gastroenteritis Outbreaks

L EDWARDS, D SHAH, K FUJII, J TOTARO, N BARKER, J ABBOTT, J CHEN, R MYERS.
Maryland Department of Health and Mental Hygiene, Baltimore, Maryland


Background: Gastroenteritis (GE) represents approximately two-thirds of all the communicable disease outbreaks reported in Maryland each year, yet the causative agent is not identified for a majority of these outbreaks. In January 2002, the Maryland Department of Health and Mental Hygiene (DHMH) began testing stool specimens for Norwalk-like viruses (NLVs) at the state health department laboratory. This evaluation was done in order to indicate the usefulness of NLV testing in Maryland.

Methods: All GE outbreaks reported in Maryland from January 1 – March 31, 2002 were compared to GE outbreaks reported from January 1 – March 31 of 1999, 2000, and 2001, respectively. Laboratory samples collected and testing results were reviewed.

Results: During the first three months of 2002, stools were tested for Norwalk-like viruses in 23 (31%) of gastroenteritis outbreaks. NLV was identified in 17 (74%) of outbreaks in which testing was attempted. This includes lab confirmation for 11 (73%) GE outbreaks at nursing homes in which person-to-person transmission was suspected, 3 (75%) foodborne GE outbreaks, and 3 (75%) GE outbreaks in other settings. Compare these figures to outbreaks during the same three months in 1999 – 2001 in which NLV was identified in an average of only 4 outbreaks each year (range= 2 - 6). NLV was isolated in 13 of 24 (57%) of GE outbreaks in which testing was offered.

Conclusions: Prior to implementation of testing for NLVs at the Maryland State Health Department, the causative agent for a majority of GE outbreaks had remained unknown. Testing for NLVs at the state level has helped Maryland identify Norwalk-like viruses as the agent for a majority of the GE outbreaks in which NLV testing was attempted. States that do not have the ability to test for NLV at the state level may want to consider offering this testing capability at their state laboratory.


Maryland Department of Health & Mental Hygiene — Epidemiology & Disease Control Program

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